In the last few years, due to the continuous use of antibiotics, microorganisms have gained multiple drug-resistance pathogenicity. Along with this problem, sometimes these commonly used drugs/antibiotics become the cause of adverse effects on a host that include depletion of the beneficial gut and mucosal microorganisms, hypersensitivity, and allergic reactions. To eliminate or at least reduce the problematic cause, there is a need to develop some alternative antimicrobial drugs for the treatment of infectious diseases.
One of the approaches to be carried on is to screen local plants for possible antimicrobial properties. The antimicrobial activities of these natural plant materials have been explored in recent years. Plant materials are still an important resource to encounter serious diseases in the world. According to WHO, herbal medicines serve the health needs of about 80% of the world’s population, especially people in rural areas who are dependent on these traditional medicines, and plant extracts are being used in traditional therapies.
These medicinal and flowering plants are rich in a wide assortment of secondary metabolites including alkaloids, tannins, flavonoids, and terpenoids which are considered to have antimicrobial activities in in-vitro studies. Therefore, new sources for the production of antibiotics are being investigated, especially the research being carried out on plant sources.
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